BDBM310898 N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide::US10150767, Example 22

SMILES CN(C)C(=O)c1cccc(c1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=YHMNROQTPUKNLA-UHFFFAOYSA-N

Data  38 IC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 310898   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain2 (unknown origin) using biotinylated ligand incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain1 (unknown origin) using biotinylated ligand incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain2 (unknown origin) using biotinylated ligand incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain1 (unknown origin) using biotinylated ligand incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB